Phone: (864) 656-0481
Office: 481 Hunter Laboratories
Clemson, SC 29634-0973
Professor, Clemson University, 2015-present
Associate Professor, Clemson University, 2009-2015
Assistant Professor, Clemson University, 2003-2009
Postdoctoral researcher with Prof. Stuart Linn, Molecular & Cellular Biology, 2001-2003
NIH postdoctoral fellow with Prof. Kenneth N. Raymond, Chemistry, 1999-2001
Ph.D., University of Illinois, Urbana-Champaign, Prof. Greg Girolami, 1999
A.B., Harvard University, 1994
Dr. Brumaghim first became interested in research chemistry as an undergraduate after conducting undergraduate research
in the laboratories of Professors George Whitesides and Andrew Barron at Harvard,
and Richard Eisenberg at the University of Rochester, primarily in synthetic inorganic chemistry.
During graduate school at the University of Illinois, she worked with Professor Greg Girolami to synthesize and characterize
air- and moisture-sensitive osmium complexes containing the pentamethylcyclopentadienyl ligand.
Seeking to focus on biological applications of inorganic chemistry, Dr. Brumaghim then began an NIH postdocotoral fellowship
with Professor Ken Raymond in the Chemistry Department at the University of California at Berkeley.
Having assiduously avoided water and oxygen during most of her graduate tenure, she now performed much of her work in
water. Using Ga(III) to mimic Fe(III), Dr. Brumaghim synthesized and resolved chiral Ga(III) hydroxamate complexes.
Drawing on her graduate training in organometallic catalysis, she also studied the incorporation of chiral phosphonium cations and
ruthenium catalysts into the Raymond supramolecular assemblies.
To gain more experience working with DNA, Dr. Brumaghim accepted a second postdoctoral research position with Professor
Stuart Linn in the Molecular and Cellular Biology department at Berkeley. There she studied the effects of iron coordination
on oxidative DNA damage and determined sites for iron localization and reduction rates for the biological reductants NAD(P)H.
As a chemistry professor at Clemson University, Dr. Brumaghim's work focuses on the biological applications of inorganic chemistry,
using a wide range of techniques to determine mechanisms of antioxidant activity and prevention of metal-mediated DNA damage.
Link to Complete Curriculum Vitae
Link to Clemson Chemistry Department's profile